Abstract:
The coronavirus disease-2019 (COVID-19) is a global pandemic which has not been seen in recent history, leaving behind deep socioeconomic damages and huge human losses with the disturbance in the healthcare sector. There are number of NP-based diagnostic systems have been reported for coronaviruses (CoVs) and specifically for SARS-CoV-2. However, extensive studies are still necessary and required for the nanoparticle (NP) based therapy. The present discussion has highlighted the different traditional therapeutic techniques, along with the potential contribution of nanomedicine against the severe acute respiratory syndrome corovirus-2 (SARS-CoV-2). Repositioning of the drugs such as remdesivir and chloroquine, is a rapid process for the reach of safe therapeutics, and the related clinical trials have determined effects against COVID-19. Various protein based SARS-CoV-2 vaccine candidates have successfully entered clinical phases, determining positive results. The possible nanovaccines usually focused on the antigenic properties of spike (S) protein and might be possible to become approachable, feasible and promising techniques in lowering the net viral burden.
Biography:
Sushil Kumar Upadhyay is Assistant Professor Biotechnology at Maharishi Markandeshwar (Deemed to be University), India with 14+ years of rich teaching-cum-research experience in Parasitology, Nanobiotechnology & Microbiology. Dr. Upadhyay has received about 2 dozens of awards including Bharat Jyoti award, Bharat Shiksha Gaurav Puraskar, Best Teacher award, Paryavaran Shri Samman, Paryavaran Ratna Puraskar, Vigyan Ratna Puraskar and felicitated many Fellow awards as FISEC, FSESc, FSSc, FSLSc, FISCA, FZSI, FAGEM, FHSI, FMERC, FBS, FSEZR, FIAZ, FGESA, FI2OR, FGT, FSAN, FSASS, FAELS, FSOE, FSSN, FABRF, FISDS (Japan), FLS (London) in yesteryears. Dr Upadhyay has served as Special Officer WCCB GoI, Global Goodwill Ambassador India (Humanitarian), Sustainable Cosmos Ambassador GTS in past years. His research skill is excellent, published 9 patents, 32 books and 145 research articles in high impact journals, and actively participated in around 285 conferences also. His contribution for economic empowerment to youths at grassroots level for livelihood and sustainability by mission “lab to land transfer of science and technology” and vision “earn as you learn” is also remarkable and can't be ignored. Dr. Upadhyay is an ideal teacher and his hard work inspires students to achieve their goal be ‘SMART’ [S=Specific, M=Meaningful, A=Achievable, R=Relevant, T=Time-bound].
