Dimple Sethi Chopra

Title : Development of herbal nanogels for treatment of burn wound infections

Abstract:

A wound result from disintegration in the defensive function of the skin. Thermal or physical damage to the skin usually involves loss of cohesiveness of the epithelium, with or without loss of underlying connective tissue. The process and duration of healing of wound are crucial factors in deciding the wound type as acute or chronic. Acute wounds heal in 8 to 12 weeks, whereas chronic wounds resulting from burns, decubitis ulcer and leg ulcer take a considerably long time to heal.  Wound Infection delays wound healing. It becomes all the more tedious in case of diabetes. Chronic wounds are huge challenge for doctors, patients, and a great economic burden for their families. Conventional Hydrocolloid dressings are not appropriate for deeper wounds, especially wounds with an infection that need oxygen to increase the healing rate of the wound. Herbal Nanogels prepared using plant extracts like Ocimum sanctum, Hypericum perforatum were found to accelerate wound healing and result in minimum scarring post treatment. Herbal nanogels are nontoxic and biocompatible and thus can be used for a long period of time. They have excellent absorption ability by virtue of their hydrophilic property. The antibacterial performance of the nanogel was evaluated using disk diffusion technique against the strains of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. 

Audience Take Away:

• Role of Nanotechnology in designing burn wound dressing.
• Burn wound infection especially non healing chronic wounds are a great economic burden.
• Health care professionals, should be trained to give immediate primary care to burn patients.
• In poor countries and rural areas, First Aid Wound Care Products should be integral part of Pressure cooker and LPG gas cylinders.
• Integral Part of Health Mission Programme of Every Nation.

Biography:

Dimple Sethi Chopra is presently working as Associate Professor in Department of  Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala. Her areas of interest are Biopharmacokinetics, molecular nanotechnology, targeted drug delivery, nanobiotechnology and nanomedicine. She is a member of American Nano Society.  She is on editorial board of many international journals. She has been granted two Indian Patents on Brain Permeable Nanoparticles. She has published several research papers innational and international journals of repute. She is an invited manuscript reviewer of many international journals like Scientific Reports. Recently she has edited book published by IGI Global “Strategies to Overcome Superbug Invasion”